Nuggets vs Spurs Prediction, Odds & Game Preview 4/2/2025

The sizzling Denver Nuggets welcome a battered San Antonio Spurs squad to Ball Arena on Wednesday night in what could be a one-sided affair given the Spurs' recent defensive collapse, allowing 121.8 points per 100 possessions over their last ten outings.

With Victor Wembanyama sidelined and both teams playing on zero rest, Nikola Jokic's dominance in the paint might prove too much for a Spurs team that's dropped four straight and seems completely outmatched.

All eyes will be on whether the league-leading Nuggets' assist machine (31.1 per game) can exploit the defensive gaps when the Denver Nuggets host the San Antonio Spurs in this Western Conference showdown.

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Denver Nuggets vs. San Antonio Spurs preview

The Nuggets look to clinch their three-game season series against the struggling Spurs when these Western Conference foes clash at Ball Arena tomorrow night, with both teams facing the challenge of playing on zero rest.

Denver's elite offense, ranked fourth in adjusted efficiency (120.1) and first in assists (31.1 per game), should feast against a San Antonio defense that's been flat-out terrible lately, surrendering at least 122 points in six of their last seven road games.

Nikola Jokić continues his dominance, coming off a monster 27-point, 14-rebound performance against Utah, while the Spurs will desperately miss Victor Wembanyama's 24.3 points and 11 rebounds per game.

San Antonio's bench showed signs of life in their embarrassing loss to Golden State, with Keldon Johnson dropping 19 points on efficient 8-of-13 shooting – their lone bright spot against a Warriors team that absolutely torched them.

The contrast in playing styles could make for an interesting matchup, with Denver loving to operate in the paint while San Antonio ranks eighth in the league in three-point attempt rate.

Denver's home-court advantage (they've won their last two games by an average of 23 points) coupled with San Antonio's pathetic defensive showing during their four-game losing streak makes this feel like a potential blowout in the making.

Watch for the battle of pace as both teams like to push the tempo – Denver averages 100.0 possessions per 48 minutes (5th) while San Antonio isn't far behind at 99.3 (13th).

The Nuggets' lackluster perimeter defense (ranked 21st in opposing three-point percentage) might be the Spurs' only path to keeping this one competitive.