The Los Angeles Dodgers look to close out their series against the St. Louis Cardinals on Wednesday at Dodger Stadium, with both National League clubs heading in opposite directions as the season enters its final stretch.
Los Angeles (66-48) sits atop the NL West and gets a premium matchup with two-way superstar Shohei Ohtani taking the mound against a Cardinals offense that ranks just 14th in runs per game.
St. Louis (57-58) remains stuck around .500 and faces an uphill battle with Matthew Liberatore on the bump, who has surrendered 54 runs across 109 innings this season.
Los Angeles Dodgers vs. St. Louis Cardinals prediction: who will win?
For tonight's Los Angeles Dodgers vs St. Louis Cardinals matchup, our predictive model gives the Dodgers a 52.5% chance of defeating the Cardinals.
Los Angeles Dodgers: 52.5% win probability
- Elite offensive production averaging 5.1 runs per game (578 runs in 113 games)
- Strong divisional position sitting first in NL West at 65-48 (.575 win percentage)
- Superior run differential of +70 compared to Cardinals' -12
St. Louis Cardinals: 47.5% win probability
- Inconsistent recent form with alternating wins and losses (WLWLL pattern)
- Mediocre .500 record (57-57) shows lack of consistency against quality competition
- Negative run differential allowing more runs (510) than they score (498)
At Sporting Post, our custom prediction model blends insights from leading MLB analysts to give you a clear edge.
Instead of sorting through endless opinions, we streamline expert picks, advanced team metrics, and market trends into one place. Our AI tracks top sources and assigns a confidence score to each prediction. These are averaged into a win probability that reflects the expert consensus. It gives you a data-backed view of what the sharpest minds in MLB expect.
Los Angeles Dodgers | St. Louis Cardinals | |
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Los Angeles Dodgers vs. St. Louis Cardinals preview
The Cardinals limp into Dodger Stadium sitting at .500 and desperately needing a spark to salvage their wild card hopes, while Los Angeles looks to put the finishing touches on another dominant NL West campaign.
Matthew Liberatore takes the hill for St. Louis carrying a troubling 4.61 ERA and having surrendered 54 runs across just 109 innings this season, facing the unenviable task of containing a Dodgers offense that ranks third in MLB at 5.12 runs per game.
On the flip side, Shohei Ohtani gets the ball for Los Angeles and brings elite two-way production to the table, boasting a stellar 2.99 career ERA while also leading the Dodgers' explosive lineup with 38 home runs and a .600 slugging percentage.
The Cardinals' offensive struggles are glaring, averaging just 4.4 runs per game with only three hitters posting an OPS+ above 100, leaving too much pressure on Ivan Herrera and Willson Contreras to carry the load.
Los Angeles counters with remarkable depth throughout their order, featuring Will Smith's .321 average, Freddie Freeman's consistent .305 clip, and Max Muncy's power threat alongside Ohtani's dynamic presence.
With the Dodgers bullpen holding a respectable 68.6% save percentage and the Cardinals sitting 22nd in runs allowed, this matchup highlights the gap between a contender and a team fighting to stay relevant.
Los Angeles Dodgers vs. St. Louis Cardinals form


Los Angeles Dodgers vs. St. Louis Cardinals head to head

Los Angeles Dodgers
33%

St. Louis Cardinals
67%
Aug 5, 2025
Los Angeles Dodgers
2 : 3
St. Louis Cardinals
Jun 8, 2025
St. Louis Cardinals
3 : 7
Los Angeles Dodgers
Jun 7, 2025
St. Louis Cardinals
2 : 1
Los Angeles Dodgers
Jun 7, 2025
St. Louis Cardinals
5 : 0
Los Angeles Dodgers
Aug 18, 2024
St. Louis Cardinals
1 : 2
Los Angeles Dodgers
Aug 17, 2024
St. Louis Cardinals
5 : 2
Los Angeles Dodgers
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