The Detroit Tigers head to Guaranteed Rate Field on Monday night looking to extend their impressive 66-50 record against a struggling Chicago White Sox team that sits at 42-73 and desperately needs wins.
This matchup features contrasting trajectories as Detroit's solid pitching staff (3.81 ERA) faces a White Sox offense that ranks 27th in runs per game at just 3.83.
With Chris Paddack taking the mound for the Tigers against Jonathan Cannon for Chicago, the betting market has installed Detroit as road favourites at -150, though the White Sox offer intriguing value as home underdogs.
Chicago White Sox vs. Detroit Tigers prediction: who will win?
For tonight's Chicago White Sox vs Detroit Tigers matchup, our predictive model gives the Tigers a 60% chance of defeating the White Sox.
Chicago White Sox: 40% win probability
- Worst record in AL at 43-75 (.364 winning percentage)
- Poor run differential (-75) with 452 runs scored vs 527 allowed
- Currently on a four-game losing streak (WLLLL recent form)
Detroit Tigers: 60% win probability
- Strong offensive production (575 runs scored ranks 2nd in AL)
- Solid win percentage (.571) shows consistent performance
- Balanced run differential (+77) indicates both offensive and defensive capability
At Sporting Post, our custom prediction model blends insights from leading MLB analysts to give you a clear edge.
Instead of sorting through endless opinions, we streamline expert picks, advanced team metrics, and market trends into one place. Our AI tracks top sources and assigns a confidence score to each prediction. These are averaged into a win probability that reflects the expert consensus. It gives you a data-backed view of what the sharpest minds in MLB expect.
| Chicago White Sox | Detroit Tigers | |
|---|---|---|
| Moneyline |
Chicago White Sox vs. Detroit Tigers preview
The Tigers head to the South Side riding momentum from their strong 66-50 record, facing a White Sox team that's endured a brutal campaign at 42-73 and sits near the bottom of the American League standings.
Chris Paddack takes the mound for Detroit with his 4.50 ERA and tendency to give up contact, while Chicago counters with Jonathan Cannon, who's struggled to a 4.87 ERA in his young career.
Detroit's offense has been quietly effective this season, averaging 4.8 runs per game with 150 home runs, but they'll need to capitalize against a White Sox pitching staff that ranks 22nd in runs allowed per nine innings.
The White Sox bullpen presents a clear weakness with just a 46.9% save percentage, ranking dead last in MLB, which could give the Tigers late-game opportunities if they can keep it close early.
Chicago's offensive struggles are well-documented, ranking 27th in runs scored at just 3.83 per game, putting even more pressure on their shaky pitching to keep them competitive.
With both starters prone to giving up hits and runs, this matchup at Rate Field could turn into the type of slugfest that favors whichever team can get timely hitting when runners are in scoring position.
Chicago White Sox vs. Detroit Tigers form
Chicago White Sox vs. Detroit Tigers head to head
Chicago White Sox
33%
Detroit Tigers
67%
Jun 5, 2025
Chicago White Sox
3 : 2
Detroit Tigers
Jun 4, 2025
Chicago White Sox
4 : 5
Detroit Tigers
Jun 3, 2025
Chicago White Sox
8 : 1
Detroit Tigers
Jun 2, 2025
Chicago White Sox
1 : 13
Detroit Tigers
Apr 6, 2025
Detroit Tigers
4 : 3
Chicago White Sox
Apr 5, 2025
Detroit Tigers
7 : 2
Chicago White Sox
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