The Tampa Bay Rays host the St. Louis Cardinals on Friday night at George M. Steinbrenner Field with both teams desperately fighting to stay in the playoff hunt.
With the Cardinals sitting at 63-65 and the Rays at 61-66, this late-August showdown could define each club's postseason hopes as veteran starters Miles Mikolas and Adrian Houser take the mound.
Tampa Bay enters as slight home favourites at -130 despite their struggles, while St. Louis looks to capitalise on a road opportunity that could flip their season's trajectory.
Tampa Bay Rays vs. St. Louis Cardinals prediction: who will win?
For tonight's Tampa Bay Rays vs St. Louis Cardinals matchup, our predictive model gives the Rays a 65.5% chance of defeating the Cardinals.
Tampa Bay Rays: 65.5% win probability
- Superior run differential with +24 compared to Cardinals' -23 (567 runs scored vs 543 allowed)
- Better divisional position sitting 4th in AL East at .477 vs Cardinals' 4th place .496 in NL Central
- Home field advantage with strong recent pitching staff allowing just 543 runs in 128 games
St. Louis Cardinals: 34.5% win probability
- Poor run differential of -23 with 588 runs allowed vs 565 scored shows defensive struggles
- Inconsistent recent form going 2-3 in last 5 games (WLWWL)
- Road disadvantage facing a Rays team that's been more efficient defensively this season
At Sporting Post, our custom prediction model blends insights from leading MLB analysts to give you a clear edge.
Instead of sorting through endless opinions, we streamline expert picks, advanced team metrics, and market trends into one place. Our AI tracks top sources and assigns a confidence score to each prediction. These are averaged into a win probability that reflects the expert consensus. It gives you a data-backed view of what the sharpest minds in MLB expect.
Rays vs. Cardinals Odds
These are the best MLB odds we found across major U.S. sportsbooks for this game.
Tampa Bay Rays | St. Louis Cardinals | |
---|---|---|
Moneyline |
Odds are based on the latest data at publication and are subject to real-time updates.
Don’t miss out on top sportsbook promos. Get more out of every bet by browsing the latest US betting sites and betting apps for 2025.
Tampa Bay Rays vs. St. Louis Cardinals preview
The Cardinals and Rays meet at George M. Steinbrenner Field with both clubs struggling through disappointing campaigns, sitting well below .500 and looking to salvage something from the final stretch.
Miles Mikolas takes the mound for St. Louis carrying a pedestrian 4.24 ERA and career 70-73 record, facing off against Tampa Bay's Adrian Houser, who brings his own mixed bag at 38-43 lifetime.
St. Louis enters this one hitting just .249 as a team while striking out nearly 1,000 times, though they've managed to keep pace offensively with Tampa Bay despite the poor contact numbers.
The Rays hold a slight edge on the mound with their 3.92 team ERA ranking 11th in baseball, compared to the Cardinals' 4.24 mark that sits near the bottom third of the league.
Tampa Bay's bullpen has been shaky in save situations, converting just 57.1% of their chances with 21 blown saves, while the Cardinals aren't much better at 63.8%.
With both teams essentially playing out the string, this matchup comes down to which starter can limit the damage against lineups that have shown flashes but lack consistency.
Tampa Bay Rays vs. St. Louis Cardinals form


Betting on the MLB?
Sporting Post is your trusted hub for MLB betting coverage. We break down expert MLB predictions and deliver today’s MLB best bets with clear, data-driven analysis. Want secure and reliable options? Explore our top picks for MLB betting sites.