The Cincinnati Reds host the St. Louis Cardinals at Great American Ball Park on Friday night as both teams battle for their postseason lives with the Reds clinging to wildcard hopes 4.5 games behind the Mets while the Cardinals look to snap a concerning two-game road skid.
Matthew Liberatore takes the mound for St. Louis carrying troubling road form after surrendering 10 runs across his last three away starts, facing Cincinnati's Zack Littell who has been far more reliable at home despite his 0-2 record and 6.55 ERA against the Cardinals historically.
With Cincinnati winning three of the last five meetings and both offenses struggling recently, this NL Central showdown could hinge on which starter can limit the damage in what projects as a low-scoring affair.
Cincinnati Reds vs. St. Louis Cardinals prediction: who will win?
For tonight's Cincinnati Reds vs St. Louis Cardinals matchup, our predictive model gives the Reds a 52% chance of defeating the Cardinals.
Cincinnati Reds: 52% win probability
- Better defensive consistency allowing 563 runs compared to Cardinals' 622
- Superior recent offensive production with 597 runs scored vs Cardinals' 588
- Home field advantage in a tight NL Central division race
St. Louis Cardinals: 48% win probability
- Struggling run prevention giving up 622 runs, 59 more than the Reds
- Inconsistent recent form going 2-3 in last 5 games (WLLWL)
- Road challenges as visiting team against division rival with playoff implications
At Sporting Post, our custom prediction model blends insights from leading MLB analysts to give you a clear edge.
Instead of sorting through endless opinions, we streamline expert picks, advanced team metrics, and market trends into one place. Our AI tracks top sources and assigns a confidence score to each prediction. These are averaged into a win probability that reflects the expert consensus. It gives you a data-backed view of what the sharpest minds in MLB expect.
Reds vs. Cardinals Odds
These are the best MLB odds we found across major U.S. sportsbooks for this game.
| Cincinnati Reds | St. Louis Cardinals | |
|---|---|---|
| Moneyline |
Odds are based on the latest data at publication and are subject to real-time updates.
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Cincinnati Reds vs. St. Louis Cardinals preview
The Cardinals limp into Cincinnati riding a brutal stretch that's seen them drop five of their last seven games, with their playoff dreams all but extinguished at 65-69.
Meanwhile, the Reds sit just 4.5 games back of a wild card spot but desperately need to turn things around after getting swept by the Dodgers to follow up a series loss to Arizona.
Matthew Liberatore takes the hill for St. Louis coming off a rough patch where he's surrendered 10 runs across his last three starts, including a four-run beating by Tampa Bay in just 4.1 innings.
Cincinnati counters with Zack Littell, who owns a respectable 3.62 ERA but has struggled historically against the Cardinals with an 0-2 record and 6.55 ERA in five career meetings.
The offensive numbers tell a tale of two middling clubs, with both teams hovering around the league average in most categories, though Elly De La Cruz continues to be the Reds' most dynamic threat with 19 homers and 77 RBI.
With Great American Ball Park hosting what could be a pivotal series for Cincinnati's postseason hopes, the pressure falls squarely on the home club to capitalize against a Cardinals squad that's lost three of four on the road.
Cincinnati Reds vs. St. Louis Cardinals form
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