The Cincinnati Reds host the St. Louis Cardinals on Saturday night at Great American Ball Park, with both NL Central clubs fighting to salvage disappointing seasons as the regular season winds down.
Cincinnati sits at 68-66 and desperately needs wins to stay in the wild card hunt, while the Cardinals at 65-69 are staring at a third straight postseason miss.
The pitching matchup favors the Reds significantly, as Andrew Abbott (3.45 expected ERA) takes the mound against struggling Cardinals starter Michael McGreevy, who has surrendered 34 runs in just 63 innings this season.
Cincinnati Reds vs. St. Louis Cardinals prediction: who will win?
For tonight's Cincinnati Reds vs St. Louis Cardinals matchup, our predictive model gives the Reds a 52% chance of defeating the Cardinals.
Cincinnati Reds: 52% win probability
- Home field advantage with strong offensive production (602 runs scored ranks 7th in NL)
- Better run differential showing balanced team strength (+32 vs Cardinals' -32)
- Recent momentum with improved form after slow stretch (1 win in last 5 but better underlying metrics)
St. Louis Cardinals: 48% win probability
- Poor run prevention allowing 627 runs (4th-worst in NL Central)
- Negative run differential of -32 indicates consistent struggles in close games
- Road struggles as visitors against division rival with home crowd disadvantage
At Sporting Post, our custom prediction model blends insights from leading MLB analysts to give you a clear edge.
Instead of sorting through endless opinions, we streamline expert picks, advanced team metrics, and market trends into one place. Our AI tracks top sources and assigns a confidence score to each prediction. These are averaged into a win probability that reflects the expert consensus. It gives you a data-backed view of what the sharpest minds in MLB expect.
Reds vs. Cardinals Odds
These are the best MLB odds we found across major U.S. sportsbooks for this game.
Cincinnati Reds | St. Louis Cardinals | |
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Moneyline |
Odds are based on the latest data at publication and are subject to real-time updates.
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Cincinnati Reds vs. St. Louis Cardinals preview
The Cardinals limp into Great American Ball Park carrying the baggage of another disappointing season, sitting second-worst in the NL Central at 67-69 and staring down a third straight postseason absence.
Michael McGreevy takes the ball for St. Louis despite allowing opponents to feast on his offerings all season, posting a brutal .293 expected batting average against and watching hitters drive in runs seemingly at will.
Cincinnati enters with slightly more hope at 68-67, though their recent skid has pushed wild card dreams further from reach just when they needed to make a move.
The Reds counter with Andrew Abbott, who has been a bright spot in an otherwise rocky campaign, limiting opponents to weak contact while racking up 118 strikeouts across 134 innings.
Both lineups present top-heavy concerns, with the Cardinals leaning heavily on Willson Contreras and Ivan Herrera while Cincinnati banks on the dynamic Elly De La Cruz to spark their offense.
This late-season clash carries the weight of fading hopes for both clubs, making every pitch crucial in what could define the final month for these NL Central neighbors.
Cincinnati Reds vs. St. Louis Cardinals form


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