Wednesday's Premier League slate offers a tantalizing mix of high-stakes matchups with Liverpool hosting Everton in a fiery Merseyside derby while Manchester City welcome Leicester City to the Etihad Stadium.
Our Premier League best bets highlight Crystal Palace's impressive form against struggling Southampton, Brighton's surprising edge over Champions League-chasing Aston Villa, and the goal-scoring prowess of standouts like Mohamed Salah and Alexander Isak.
Read on for our expert analysis and Premier League picks that deliver value across multiple markets including correct scores, anytime goalscorers, and both teams to score opportunities.
Premier League betting tips
| Game | Time | Pick |
|---|---|---|
 @ | 7:45 PM | |
 @ | 7:45 PM | |
 @ | 8:00 PM |
