Saturday's Premier League action offers several high-value betting opportunities across the slate, with Manchester City's visit to Southampton standing out as a prime target for bettors.

City have kept clean sheets in five of their last seven matches and face a Saints side showing minimal attacking threat, making City to win to nil at 13/10 particularly appealing.

Meanwhile, Brentford's trip to Ipswich Town presents another strong betting angle with the Bees riding a three-match winning streak against hosts who've lost seven straight at home.

Premier League betting tips

GameTimePick
Southampton logoManchester City logo
3:00 PMManchester City to Win to Nil (13/10)|Kevin De Bruyne to Score Anytime (2/1)
Ipswich logoBrentford logo
3:00 PMBrentford to Win (8/13)|Yoane Wissa to Score Anytime (11/8)

Southampton vs. Manchester City

Manchester City have been in stellar defensive form lately, keeping clean sheets in five of their last seven matches across all competitions.

This defensive solidity has coincided with their annual title push, where Guardiola's men typically tighten up at the back when it matters most.

They now face a Southampton side that showed minimal attacking threat in their recent 2-0 defeat to Leicester, a team with far less defensive quality than City.

The Saints are already relegated and likely demoralized, making them prime candidates to struggle against City's organized defensive setup.

With City still in a tight title race with Arsenal, expect their full focus and a professional performance where they control the game without conceding.

Kevin De Bruyne has a remarkable record against Southampton, contributing to more goals against them than any other Premier League side.

His stats against the Saints are impressive – five goals and eleven assists in fifteen appearances across all competitions.

De Bruyne's set-piece expertise and long-range shooting ability make him particularly dangerous against a vulnerable Southampton defense.

The Belgian playmaker has returned to form after his injury layoff earlier in the season, reclaiming his role as City's creative and attacking fulcrum.

Against already-relegated Southampton, De Bruyne should find space to operate between the lines and capitalize on scoring opportunities.

Ipswich vs. Brentford

Brentford come into this fixture in red-hot form, riding a three-match winning streak that's kept their European qualification hopes alive.

They face an Ipswich side with a dismal home record, having picked up just seven of their total 22 points at Portman Road this season.

Even more concerning for Ipswich fans is their current home form – they've lost each of their last seven matches at Portman Road.

Brentford have been finding the net consistently on the road, scoring multiple goals in recent away fixtures, which should trouble Ipswich's vulnerable defense.

With European qualification still a possibility, Brentford have everything to play for, while newly-promoted Ipswich may already have one eye on next season.

Yoane Wissa has been in exceptional scoring form, netting in four consecutive matches coming into this fixture.

His goal against Manchester United last weekend showcased his confidence and sharpness in front of goal, qualities that should trouble Ipswich's fragile defense.

With 18 Premier League goals this season, Wissa has established himself as Brentford's primary goal threat and a consistent performer.

Ipswich have struggled defensively at home, conceding multiple goals in many of their Portman Road defeats this season.

Given his current scoring streak and Ipswich's defensive frailties, Wissa is perfectly positioned to extend his impressive goal-scoring run.

Best Premier League sportsbook promos

Start OddsCheckerWidget (lazyOnload)
End OddsCheckerWidget (lazyOnload)