The Cleveland Guardians head to Chicago as -128 favourites against a White Sox team desperate to salvage something from a brutal 42-72 season when these AL Central rivals clash on Friday night at Rate Field.
Cleveland sits at 59-55 and needs every win to stay competitive in what's shaping up as a tight playoff race, while Chicago has been one of baseball's biggest disappointments with the second-worst record in the league.
With Tanner Bibee taking the mound for the Guardians against Aaron Civale for the White Sox, this matchup presents solid value on both sides of a line that's moved throughout the week.
Chicago White Sox vs. Cleveland Guardians prediction: who will win?
For tonight's Chicago White Sox vs Cleveland Guardians matchup, our predictive model gives the White Sox a 53.5% chance of defeating the Guardians.
Chicago White Sox: 53.5% win probability
- Home field advantage in crucial divisional clash (playing at guaranteed rate field)
- Recent momentum with win breaking four-game losing streak (LLLLW recent form)
- Desperate team with nothing to lose mentality sitting in last place (42-73 record)
Cleveland Guardians: 46.5% win probability
- Road struggles as division leaders often face extra pressure (59-55 overall record suggests inconsistency)
- Offensive production concerns with lowest run total in AL Central (450 runs scored vs 473 allowed)
- Recent inconsistent form despite wins (WWWLW shows vulnerability)
At Sporting Post, our custom prediction model blends insights from leading MLB analysts to give you a clear edge.
Instead of sorting through endless opinions, we streamline expert picks, advanced team metrics, and market trends into one place. Our AI tracks top sources and assigns a confidence score to each prediction. These are averaged into a win probability that reflects the expert consensus. It gives you a data-backed view of what the sharpest minds in MLB expect.
Chicago White Sox | Cleveland Guardians | |
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Chicago White Sox vs. Cleveland Guardians preview
The White Sox return home to Rate Field on Friday night desperately needing any spark they can find, sitting at a dismal 42-72 while the Guardians come to town with momentum at 59-55 and still very much in playoff contention.
Cleveland's offense has been a struggle all season, ranking 26th in baseball with just 4.0 runs per game despite solid pitching that's kept them competitive with a 3.83 team ERA.
Chicago's season has been defined by pitching woes, surrendering 4.60 runs per nine innings while their offense isn't much better at 3.83 runs scored per contest.
The pitching matchup features Tanner Bibee for Cleveland, who brings a respectable 3.62 ERA and solid strikeout ability, against Aaron Civale making his return to face his former club after being traded from the Guardians.
Both bullpens have had their issues this year, with Chicago's relief corps particularly shaky at just a 46.9% save rate compared to Cleveland's more reliable 68.0%.
This division rivalry takes on added significance for the Guardians, who need every win they can get to stay in the AL Central race while the White Sox are simply playing out the string on what's been a lost season.
Chicago White Sox vs. Cleveland Guardians form


Chicago White Sox vs. Cleveland Guardians head to head

Chicago White Sox
17%

Cleveland Guardians
83%
Jul 13, 2025
Chicago White Sox
5 : 6
Cleveland Guardians
Jul 12, 2025
Chicago White Sox
2 : 6
Cleveland Guardians
Jul 12, 2025
Chicago White Sox
5 : 4
Cleveland Guardians
Jul 11, 2025
Chicago White Sox
2 : 4
Cleveland Guardians
Apr 10, 2025
Cleveland Guardians
6 : 1
Chicago White Sox
Apr 9, 2025
Cleveland Guardians
3 : 2
Chicago White Sox
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